New power and sensors are the urgent demands for the fast-developing wearable sensors, implantable biosensors, things of internet and other micro/nano sensors network. Energy harvesting technology gives a promising way for the power challenge. New principle functional devices provide new choices for every kind of sensors. In this lecture, the development progress of nanogenerator will be talked firstly, and then some works on fiber-based nanogenerator, ACZnOnanowire nanogenerator, integratedZnOnanowire nanogenerator, ferroelectric piezoelectric nanowire nanogenerator, non-contact mechanical energy harvesting nanogenerator, implantable nanogenerator and some new developed nanogenerators will be talked. After that, some nanodevices based onpiezotronicprinciple will be discussed.